RR445 - An evaluation of chemical disinfecting agents used in endoscopy suites in the NHS
This research report looks at alternatives to glutaraldehyde for the disinfection of endoscopes. It highlights their benefits and limitations.
The work was commissioned because of the historically high number of cases of occupational asthma caused by glutaraldehyde.
There is no single system for disinfection and no single most appropriate disinfectant. Many users are moving away from glutaraldehyde towards other products, some of which are regarded as potential asthmagens.
The report presents the control approaches for disinfecting agents based on HSE's COSHH Essentials. This is summarised as follows:
| Chemical Base | Example of Product | COSHH Essentials Hazard Group | COSHH Essentials Control Approach |
|---|---|---|---|
| Chlorine base | Sterilox | A (low hazard) | 1 (general ventilation) |
| Chlorine base | Tristel | A (low hazard) | 1 (general ventilation) |
| Peroxygen | Virkon S (1% liquid) | A (low hazard)* | 1 (general ventilation) |
| Peracetic Acid | Nu-Cidex/Aperlan | C (medium hazard)* | 3 (containment) |
| Ortho-phthalaldehyde | Cidex-OPA | C (medium hazard)* | 3 (containment) |
| 2% Glutaraldehyde | Cidex | E (special case) | 4 (special case) |
*Cidex-OPA is subject to requirement for self-classification within EU legislation. This assessment is based on manufacturer data.
This report and the work it describes were funded by the Health and Safety Executive (HSE). Its contents, including any opinions and/or conclusions expressed, are those of the author alone and do not necessarily reflect HSE policy.
Visit the RR445 report (PDF) [12]
The Research Report Series are produced in Adobe Acrobat. The use of the latest version of the software is recommended which is available at the Adobe website via the link on this page.
Assistance in the use of Adobe Acrobat PDF files is available on our FAQs[13] page.